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Year : 2015  |  Volume : 1  |  Issue : 5  |  Page : 181-182

Acute Lymphoblastic Leukemia with Normal Platelet Count

Department of Pathology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India

Correspondence Address:
Khushboo Dewan
Department of Pathology, Lady Hardinge Medical College and Associated Hospitals, 26, Amit Apartments, Sector-13, Rohini, New Delhi 110085
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2395-3977.168576

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B-acute lymphoblastic leukemia (B-ALL) often presents with pancytopenia/bicytopenia, with thrombocytopenia being the most important parameter. The case of a 12-year-old child with bicytopenia on peripheral smear was presented. On bone marrow examination, 85% morphologically lymphoid blasts, negative for myeloperoxidase, and periodic-acid Schiff on cytochemistry were found. The blasts suppressed the erythroid population but not the megakaryocytic population. On flow cytometry, a diagnosis of common-ALL-antigen positive B-precursor ALL was concluded. To conclude, ALL cannot be excluded in patients who present with a normal platelet count. A bone marrow aspirate is crucial in patients with bi/pancytopenia.

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