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Year : 2016  |  Volume : 2  |  Issue : 1  |  Page : 21-28

Quantum Dot-based Immunohistochemistry for Pathological Applications

1 Department of Gynecologic Oncosurgery, Jilin Provincial Cancer Hospital, Changchun, Jilin, China
2 Department of Colorectal Surgery, Jilin Provincial Cancer Hospital, Changchun, Jilin, China
3 Department of Ultrasonography, Jilin Provincial Cancer Hospital, Changchun, Jilin, China
4 Department of Neurosurgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
5 Clinical Laboratory, Jilin Provincial Cancer Hospital Changchun, Changchun, Jilin, China
6 Department of Biomedical Engineering, Shenzhen University, Shenzhen, Guangdong, China

Correspondence Address:
Peng Guo
Department of Biomedical Engineering, Shenzhen University, 3688 Nanhai Road, Shenzhen 518060, Guangdong
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2395-3977.177562

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Quantum dots (QDs) are novel light emitting semiconductor nanocrystals with diameter ranging from 2 to 20 nm. In comparison with traditional organic dyes and fluorescent proteins, QDs possess unique optical properties including extremely high fluorescence efficiency and minimal photobleaching which make them emerge as a new class of fluorescent labels for molecular imaging and biomedical analysis. Herein, recent advances in fundamental mechanisms and pathological applications of QD were reviewed.

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