November-December 2017| Vol 3| Issue 6
Markerless four-dimensional-cone beam computed tomography projection-phase sorting using prior knowledge and patient motion modeling: A feasibility study
Lei Zhang, Yawei Zhang, You Zhang, Wendy B Harris, Fang-Fang Yin, Jing Cai, Lei Ren
Aim: During cancer radiotherapy treatment, on-board four-dimensional-cone beam computed tomography (4D-CBCT) provides important patient 4D volumetric information for tumor target verification...
The producing capabilities of Interferon-γ and Interleukin-10 of spleen cells in primary and metastasized oral squamous cell carcinoma cells-implanted mice
Yasuka Azuma, Masako Mizuno-Kamiya, Eiji Takayama, Harumi Kawaki, Toshihiro Inagaki, Eiichi Chihara, Yasunori Muramatsu, Nobuo Kondoh
Aim: The aim of this study is to compare the immunomodulatory effects exerted by primary versus metastasized oral squamous cell carcinoma (OSCC) cells.
Methods: Mouse OSCC cell line S...
“Eating” Cancer cells by blocking CD47 signaling: Cancer therapy by targeting the innate immune checkpoint
Yi-Rong Xiang, Li Liu
Differing from the adaptive immune checkpoint mediated by programmed cell death-1 (PD-1) PD-1-ligand or CTLA-4, the CD47 and signal regulatory protein α (SIRPα) axis is emerging as a novel...
Glycosylation is involved in malignant properties of cancer cells
Kazunori Hamamura, Koichi Furukawa
Cancer cells express unique carbohydrate structures in glycoproteins and glycolipids, and their structures have been considered to be cancer-associated antigens. However, the involvement of their an...
Biomarkers in molecular epidemiology study of oral squamous cell carcinoma in the era of precision medicine
Qing-Hao Zhu, Qing-Chao Shang, Zhi-Hao Hu, Yuan Liu, Bo Li, Bo Wang, An-Hui Wang
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Oral cancer, which occurs in the mouth, lips, and tongue, is a multifactorial disease whose etiology involves environment, genetic, and epigenetic factors. Tobacco use and alcohol consumption are re...
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