March-April 2016| Vol 2| Issue 2
Etiological Trends in Oral Squamous Cell Carcinoma: A Retrospective Institutional Study
Varsha Salian, Chethana Dinakar, Pushparaja Shetty, Vidya Ajila
Aim: Oral squamous cell carcinomas (OSCCs) are among the most common cancers that affect human population worldwide. This study aims to analyze the epidemiology, risk factors, clinical and hist...
Effect of Irinotecan Combined with Cetuximab on Liver Function in Patients with Advanced Colorectal Cancer with Liver Metastases
Liang Yan, Li Yang, Xin Li, Jianfu Zhao
Aim: To explore the effect of irinotecan combined with cetuximab on liver function of advanced colorectal cancer patients with liver metastases.
Methods: A total of 97 advanced colorec...
The Role of Precision Medicine in Pancreatic Cancer: Challenges for Targeted Therapy, Immune Modulating Treatment, Early Detection, and Less Invasive Operations
Khaled Kyle Wong, Zhirong Qian, Yi Le
Pancreatic cancer is one of the most lethal types of cancer due to its heterogeneous nature and the difficulty of detecting lesions in the pancreas during the early stages of tumorigenesis. Until rece...
Targeting Signal Transducer and Activator of Transcription 3 for Colorectal Cancer Prevention and Treatment with Natural Products
Weidong Li, Cihui Chen, Zheng Liu, Baojin Hua
Signal transducers and activators of transcription 3 (STAT3), a transcription factor, plays key role in regulating the signal transduction events mediated by cytokines and growth factors. STAT3 is inv...
The Potential of Wnt Signaling Pathway in Cancer: A Focus on Breast Cancer
Mahnaz M Kazi, Trupti I Trivedi, Toral P Kobawala, Nandita R Ghosh
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Cancer development and progression as well as tumor recurrence are largely due to the presence of cancer stem cells (CSCs) that are maintained through various pathways. Wnt/β-catenin signaling is...
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