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Current Issue

January-February 2017| Vol 3| Issue 1

Original Article

Genome-wide transcriptome analysis of prostate cancer tissue identified overexpression of specific members of the human endogenous retrovirus-K family
Behnam Sayanjali

Aim: Human endogenous retroviruses (HERVs) are integrated into the human genome and represent 8% of the total genome. A retrovirus is the most complete retroelement and is characterized by ...


Original Article

Clinical utility of interleukin-18 in breast cancer patients: A pilot study
Reecha A Parikh, Toral P Kobawala, Trupti I Trivedi, Mahnaz M Kazi, Nandita R Ghosh

Aim: The aim of this study is to analyze the protein expression of interleukin 18 (IL-18) in patients with untreated breast cancer and further to evaluate its clinical efficacy in predicting tr...


Review

Current and future systemic treatment options for advanced soft-tissue sarcoma beyond anthracyclines and ifosfamide
Nadia Hindi, Javier Martin-Broto

Sarcomas are rare, life-threatening, malignant tumors. Surgery is the cornerstone of therapy in the localized setting. About one-third of patients develop distant metastasis. In the metastatic setting...


Mini Review

The genomic organization and function of IRX1 in tumorigenesis and development
Pengxing Zhang, Hongwei Yang, Xin Wang, Liang Wang, Yingduan Cheng, Yongsheng Zhang, Yanyang Tu

Iroquois homeobox (IRX), containing transcription factor family of homologous genes and proteins, is widely expressed in both vertebrates and invertebrates embryonic tissue expression profiles. They p...

Mini Review

Stem cell-based approach in diabetes and pancreatic cancer management
Yi-Zhou Jiang, Demeng Chen

Stem cell-mediated therapy is a promising strategy for treating pancreatic diseases such as Type-1 diabetes (T1D) and pancreatic cancers. Although islet transplantation has been reported to be an effe...

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Cancer Translational Medicine is an open-access and peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s free full text is available online at http://www.cancertm.com

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