September-October 2016| Vol 2| Issue 5
Correlation between paclitaxel Tc > 0.05 and its therapeutic efficacy and severe toxicities in ovarian cancer patients
Shuyao Zhang, Muyin Sun, Yun Yuan, Miaojun Wang, Yuqi She, Li Zhou, Congzhu Li, Chen Chen, Shengqi Zhang
Aim: Although paclitaxel (PTX) is a widely used chemotherapeutic agent across many cancer types, the correlation between its concentration and treatment efficacy and toxicity is yet to be clari...
Identifying gaps and relative opportunities for discovering membrane proteomic biomarkers of triple-negative breast cancer as a translational priority
Triple-negative breast cancer (TNBC) remains a significant clinical and scientific challenge. The classification of TNBC is based on the lack of expression of the human epidermal growth factor 2, the ...
The molecular mechanism and regulatory pathways of cancer stem cells
Zhen Wang, Hongwei Yang, Xin Wang, Liang Wang, Yingduan Cheng, Yongsheng Zhang, Yanyang Tu
Malignant cancer is among the top of the life-threatening conditions, challenging humanity for a long time. Traditional methods of cancer therapy include surgery, chemotherapy, and radiotherapy, which...
Nanoparticle drug delivery systems and three-dimensional cell cultures in cancer treatments and research
Wenjin Shi, Ding Weng, Wanting Niu
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Being a great threat to human health, with no permanent cure yet, better treatment and further research in cancer are inevitable. Nanoparticle drug delivery systems (NDDSs), especially pH-sensitive ND...
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