May-June 2017| Vol 3| Issue 3
Novel molecular multilevel targeted antitumor agents
Poonam Sonawane, Young A Choi, Hetal Pandya, Denise M Herpai, Izabela Fokt, Waldemar Priebe, Waldemar Debinski
Aim: A multifunctional fusion protein, IL-13.E13K-D2-NLS, effectively recognizes glioblastoma (GBM) cells and delivers its portion to the cell nucleus. IL-13.E13K-D2-NLS is composed of a cancer...
Fish oil and prostate cancer: Effects and clinical relevance
Pei Liang, Michael Gao
Men who intake high ratios of fish oil or omega-3 fatty acids (FAs), especially docosahexaenoic acid and eicosapentaenoic acid, relative to omega-6 arachidonic acid have been found to have a decreased...
Stemness-related markers in cancer
Wenxiu Zhao, Yvonne Li, Xun Zhang
Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth, and resistanc...
Autophagy regulated by miRNAs in colorectal cancer progression and resistance
Andrew Fesler, Hua Liu, Ning Wu, Fei Liu, Peixue Ling, Jingfang Ju
The catabolic process of autophagy is an essential cellular function that allows for the breakdown and recycling of cellular macromolecules. In recent years, the impact of epigenetic regulation of aut...
Gastric metastases mimicking primary gastric cancer: A brief literature review
Simona Gurzu, Marius Alexandru Beleaua, Laura Banias, Ioan Jung
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Gastric cancer is the fifth most common cancer worldwide, with most cases presenting in the form of primary tumors. In this paper, we performed a literature review on the incidence and particularities...
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