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Current Issue

March-April 2017| Vol 3| Issue 2

Original Article

Mutation detection with a liquid biopsy 96 mutation assay in cancer patients and healthy donors
Aaron Yun Chen, Glenn D Braunstein, Megan S Anselmo, Jair A Jaboni, Fernando Troy Viloria, Julie A Neidich, Xiang Li, Anja Kammesheidt

Aim: Detection of circulating tumor DNA (ctDNA) holds promise as an adjunct to traditional cancer screening methods. To determine the sensitivity and specificity of ctDNA measurements, levels w...


Review

The application of estrogen receptor-1 mutations' detection through circulating tumor dna in breast cancer
Binliang Liu, Yalan Yang, Zongbi Yi, Xiuwen Guan, Fei Ma

Breast cancer is the most common cancer in women worldwide. Endocrine therapy is the cornerstone of treatment for patients with hormone receptor-positive advanced breast cancer. Unfortunately, althoug...


Mini Review

Circulating micrornas and long noncoding rnas: Liquid biomarkers in thoracic cancers
Pablo Reclusa, Anna Valentino, Rafael Sirera, Martin Frederik Dietrich, Luis Estuardo Raez, Christian Rolfo

Thoracic cancers are the leading causes of cancer-related deaths worldwide. Recent advances in genome and transcriptome analysis have allowed for the identification of numerous classes of noncoding RN...


Mini Review

Exosomes biology: Function and clinical implications in lung cancer
Martin Frederik Dietrich, Christian Rolfo, Pablo Reclusa, Marco Giallombardo, Anna Valentino, Luis E Raez

Lung cancer is the most common malignancy in the United States, totaling 225,000 cases per year. In recent years, several new treatment options have become available based on the molecular and cellula...

Mini Review

Circulating tumor DNA: A potential biomarker from solid tumors' monitor to anticancer therapies
Ting Chen, Rongzhang He, Xinglin Hu, Weihao Luo, Zheng Hu, Jia Li, Lili Duan, Yali Xie, Wenna Luo, Tan Tan, Di-Xian Luo

Circulating tumor DNA (ctDNA) in the peripheral blood is a liquid biopsy that contains representative tumor information including gene mutations. ctDNA is a promising new avenue for real-time monitori...

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DOAJ

Cancer Translational Medicine is an open-access and peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s free full text is available online at http://www.cancertm.com

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